In order to analyze the evolutional laws of river water and sediment in the cold region of Northeast China and predict the changing trend of water and sediment, according to the measured data of runoff and sediment of the hydrological stations, a compound WD-WNN-LSTM model suitable for the characteristics of rivers in the Northeast cold region was establish, and compared with LSTM model and WNN model. The study shows that, the compound model performs better on the accuracy of annual runoff and sediment prediction, which is suitable for the simulation of water and sediment of the rivers in the cold region of Northeast China.