The method of sample field flood calculation was adopted to analyze and establish the design flood calculation empirical formula for theZuli River Basin in the West China. And the design calculation results were analyzed by comparising with the design calculation results of P-IIIfrequency curve, and the calculation accuracy of the results is high. The result chart and checklist of design flood calculation of the watershed canprovide technical support for the design flood calculation for the Zuli River Basin.