The process simulation of unsaturated zone and saturated zone can represent 4 early-warning factors, which cover the whole groundwater system. The process simulation of unsaturated zone combined with the process simulation of saturated zone is the method of groundwater pollution early -warning based on process simulation. This paper chose the Liguanpu water source as the study area, made process simulation of unsaturated zone saturated zone based on Hydrus-1D and Visual Modflow, and determined the critical value for early warning according to the complexity of the unconfined aquifer and confined aquifer. The results show that the contaminant plume increase with the time, and the maximum concentration of the plume and water source well also increased in both unconfined aquifer and confined aquifer. This paper proposed different critical values of early-warning for unconfined aquifer and confined aquifer, and the early-warning level of confined aquifer is higher than unconfined aquifer with the passage of time. The relationships between the maximum concentrations of unconfined aquifer and confined aquifer with time are linear and exponential, which can be used for the early-warning in the long time. This paper also proposed that monitoring and preventing will be taken as the principal thing in the management strategies for the first-level and zeroth-level early-warning areas, and controlling and monitoring be taken as the principal thing in the management strategies for the forth-level, third-level and secondlevel early-warning areas.