Real-time monitoring of suspended sediment concentration is an important foundation for the scientific scheduling of the Three Gorges Reservoir. More than 1,500 times comparative tests between the traditional equipment and nephelometry turbidimeter have been conducted by the Bureau of Hydrology, Changjiang Water Resources Commission. The non -linear regression models for the conversion between turbidity and suspended sediment concentration (Hereinafter referred to as SSC) and the accuracy assessment system have been proposed in this study. The results show that the proposed non-linear regression models have a number of special features such as time-sensitive, stable performance and high automatism. Furthermore, the change processes of the SSC values calculated by the proposed models are very similar with the traditional method. The calculated values of the peak SSC or sediment runoff of one flood process have high accuracy, which can provide the technical support for the scientific scheduling of the Three Gorges Reservoir.