Based on outputs from 7 models that participate in CMIP5 under Representative Concentration Pathway (RCP) scenarios, to analyze and estimate the temperature and precipitation in the 7 regions of China using yearly, seasonal, monthly datasets. The results show that warming is expected in all regions of China and the linear trend of N, ENW, WNW and Tibet is higher than others under the RCP scenarios from 2010 to 2099, with the temperature in autumn and winter show greater warming than in spring, especially in January, August, September, November and December. The trend of temperature for RCP8.5 is higher than the trend for RCP4.5 in most of the regions. It is noted that the temperature in NE will be cool during 2060-2099 under RCP4.5. The regional averaged precipitation will increase, present decreasing from the southeast to the northwest, and more stronger in spring and summer while weaker in winter. The linear trend of precipitation in WNW is the smallest in all the regions. North of the Yellow River precipitation trend is smaller, while the centre of precipitation is in the south of the Yangtze River in spring and summer, especially in May, June, July and August. In autumn, the trend in SE is lower and equal to the averaged level in China under RCP4.5, RCP8.5, respectively, and the slope of temperature is higher than others in NE, N, ENW. It is noted that precipitation will decrease in SW during 2010-2039 under RCP8.5.