Alxa Plateau, located in the monsoon margin area, where ecological environment is extremely fragile, is very sensitive tothe dry and wet changes of climate. In this paper, the mutation and its change trend was analyzed by using Mann-Kendall andMann-Whitney test, according to the monthly temperature and precipitation from the meteorology stations in the study area over therecent 60 years. The results show that the temperature mutation of the study area occurred in 1988, and the annual meantemperature from 1988 to 2010 is 1℃ higher than that from 1955 to 1987, which show a significant warming trend while there is noobvious increasing trend of annual precipitation. Although there was a slight increase trend since 1991 at some stations , theprecipitation mutation of regional scale did not occur. So the climate condition is still warm and dry , and it hasn’t changed towarm and wet.