Taking Miyi County as an example, in view of the most stringent total water resources control and the characteristics of the natural-social water cycle system in the county, a general water resources dispatching and allocation (GWAS) model for independent water supply and reservoir group joint dispatching in different regions is constructed by taking the minimum overall water shortage rate and the regional spatial balance as the objective functions, and the total amount control, water supply capacity, and quality water supply as the constraints, and using the non-dominant genetic algorithm to improve the time-space two-level elite strategy, Solve the space balanced scheduling scheme. The research shows that spatial equilibrium regulation and strong water-saving constraints significantly affect the allocation mechanism of each water use unit; Compared with the water allocation of the two schemes of independent water supply and joint regulation of reservoir groups, the largest water shortage rate of water supply in the district is Bai Po Yi Township, and the water shortage rate of each township in the joint regulation of reservoir groups is significantly reduced, with a smaller difference in water shortage. The allocation of water resources in reservoir group joint transfer is fair, and the difference of water shortage rate between units in space is small, basically realizing the balance of regional water resources supply and demand under dynamic changes.